Article
Computation of haplotypes on SNPs subsets: advantage of the "global method".
BMC genetics - 26 Oct 2006
Coulonges Cédric, Delaneau Olivier, Girard Manon, Do Hervé, Adkins Ronald, Spadoni Jean-Louis, Zagury Jean-François
Abstract excerpt
BACKGROUND: Genetic association studies aim at finding correlations between a disease state and genetic variations such as SNPs or combinations of SNPs, termed haplotypes. Some haplotypes have a particular biological meaning such as the ones derived from SNPs located in the promoters, or the ones derived from non synonymous SNPs. All these haplotypes are "subhaplotypes" because they refer only to a part of the...
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