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Article

Pleiotropic effects of a relC mutation in Streptomyces antibioticus.

Journal of bacteriology - 1 Apr 1991

Kelly K S, Ochi K, Jones G H

Abstract excerpt

Ochi (Agric. Biol. Chem. 51:829-835, 1987) has isolated a relaxed mutant of Streptomyces antibioticus, designated relC49, relC49 accumulates significantly lower levels of ppGpp than the parent stain, IMRU3720. At its maximum, the ppGpp level in relC49 was only one-fourth that observed in strain IMRU3720. Interestingly, a burst of ppGpp synthesis between 18 and 22 h of growth in IMRU3720 coincided with the onset...

Topics

Dactinomycin
Gene Expression Regulation, Bacterial
Guanosine Tetraphosphate
Mutation
Oxidoreductases
RNA, Bacterial
RNA, Messenger
Ribosomes
Streptomyces antibioticus

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1706704
DOI: 10.1128/jb.173.7.2297-2300.1991
PMCID: PMC207782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1706704-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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