Article
Streptomyces relC mutants with an altered ribosomal protein ST-L11 and genetic analysis of a Streptomyces griseus relC mutant.
Journal of bacteriology - 1 Jul 1990
Ochi K
Abstract excerpt
Several relaxed (rel) mutants have been obtained from Streptomyces species by selecting colonies resistant to thiopeptin, an analogue of thiostrepton. Using two-dimensional gel electrophoresis, I compared the ribosomal proteins from rel and rel+ pairs of S. antibioticus, S. lavendulae, S. griseoflavus, and S. griseus. It was found that all of the Streptomyces rel mutants thus examined had an altered or missing...
Topics
- Anti-Bacterial Agents
- Antimicrobial Cationic Peptides
- Crosses, Genetic
- Drug Resistance, Microbial
- Electrophoresis, Gel, Two-Dimensional
- Erythromycin
- Genotype
- Kinetics
- Membrane Fusion
- Mutation
- Peptides
