A relaxed (rel) mutant of Streptomyces coelicolor A3(2) with a missing ribosomal protein lacks the ability to accumulate ppGpp, A-factor and prodigiosin.

doi:10.1099/00221287-136-12-2405

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Article

A relaxed (rel) mutant of Streptomyces coelicolor A3(2) with a missing ribosomal protein lacks the ability to accumulate ppGpp, A-factor and prodigiosin.

Journal of general microbiology - 1 Dec 1990

Ochi K

Abstract excerpt

A relaxed (rel) mutant was found among 70 thiopeptin-resistant isolates of Streptomyces coelicolor A3(2) which arose spontaneously. The ability of the rel mutant to accumulate ppGpp during Casamino acid deprivation was reduced 10-fold compared to the wild-type. Analysis of the ribosomal proteins...

Topics

Anthraquinones
Bacterial Proteins
Chromatography, High Pressure Liquid
Drug Resistance, Microbial
Electrophoresis, Polyacrylamide Gel
Glycoside Hydrolases
Guanosine Tetraphosphate
Kinetics
Mutation
Nucleotides
Phenotype
Prodigiosin
Ribosomal Proteins
Streptomyces

Source

Open in PubMed

Identifiers

PMID: 2079628
DOI: 10.1099/00221287-136-12-2405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2079628-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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