Article
Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland.
Proceedings of the National Academy of Sciences of the United States of America - 7 Nov 2006
Mussi Paola, Liao Lan, Park Seong-Eun, Ciana Paolo, Maggi Adriana, Katzenellenbogen Benita S, Xu Jianming, O'Malley Bert W
Abstract excerpt
Estrogen receptor (ER)-mediated gene expression plays an essential role in mammary gland morphogenesis, function, and carcinogenesis. The repressor of ER activity (REA) is an ER-interactive protein that counterbalances estrogen-induced ER transcriptional activity. Our previous study showed that g...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
