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Article

DNA binding by estrogen receptor-alpha is essential for the transcriptional response to estrogen in the liver and the uterus.

Molecular endocrinology (Baltimore, Md.) - 1 Oct 2009

Ahlbory-Dieker Dörthe L, Stride Brenda D, Leder Gabriele, Schkoldow Jenny, Trölenberg Susanne, Seidel Henrik, Otto Christiane, Sommer Anette, Parker Malcolm G, Schütz Günther, Wintermantel Tim M

Abstract excerpt

The majority of the biological effects of estrogens in the reproductive tract are mediated by estrogen receptor (ER)alpha, which regulates transcription by several mechanisms. Because the tissue-specific effects of some ERalpha ligands may be caused by tissue-specific transcriptional mechanisms of ERalpha, we aimed to identify the contribution of DNA recognition to these mechanisms in two clinically important...

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Identifiers

PMID: 19574448
DOI: 10.1210/me.2009-0045
PMCID: PMC5419145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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