Article
In-vitro functional phenotypes of plasma cell lines from patients with multiple myeloma.
Leukemia & lymphoma - 1 Sept 2006
Silvestris Franco, Cafforio Paola, Calvani Nicola, De Matteo Monica, Lombardi Lucia, Dammacco Franco
Abstract excerpt
Seven plasma cell lines from patients with smoldering (group A) and overt myeloma (group B) were investigated for both phenotypic markers and in-vitro properties, including sensitivity to apoptosis, cytotoxicity, cell adhesion, chemotaxis and bone interaction. Cell lines from group A underwent apoptosis whereas those from group B were apparently resistant, promoted cytotoxicity in target cells and enhanced both...
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