Article
The generation and regulation of functional diversity of malignant plasma cells.
Cancer research - 1 Sept 2006
Nadav Liat, Katz Ben-Zion, Baron Shoshana, Cohen Nir, Naparstek Elizabeth, Geiger Benjamin
Abstract excerpt
Cellular diversity, which is a hallmark of malignancy, can be generated by both genetic and nongenetic mechanisms. We describe here variability in the adhesive and migratory behavior of malignant plasma cell populations, including multiple myeloma-derived lines and primary patient samples. Examination of the plasma cell lines ARH-77, CAG, and AKR revealed two distinct subpopulations of cells, one displaying...
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