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Article

p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.

Molecular and cellular biology - 1 Aug 2003

Cotteret Sophie, Jaffer Zahara M, Beeser Alexander, Chernoff Jonathan

Abstract excerpt

Pak5 is the most recently identified and least understood member of the p21-activated kinase (Pak) family. This kinase is known to promote neurite outgrowth in vitro, but its localization, substrates, and effects on cell survival have not been reported. We show here that Pak5 has unique properties that distinguish it from all other members of the Pak family. First, Pak5, unlike Pak1, cannot complement an STE20...

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Source

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Identifiers

PMID: 12897128
DOI: 10.1128/MCB.23.16.5526-5539.2003
PMCID: PMC166342

Genes

BAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.PMID 12897128Read ↗

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