Article
Sequence changes in both flanking sequences of a pre-tRNA influence the cleavage specificity of RNase P.
Journal of molecular biology - 20 Feb 1991
Krupp G, Kahle D, Vogt T, Char S
Abstract excerpt
The cleavage specificities of the RNase P holoenzymes from Escherichia coli and the yeast Schizosaccharomyces pombe and of the catalytic M1 RNA from E. coli were analyzed in 5'-processing experiments using a yeast serine pre-tRNA with mutations in both flanking sequences. The template DNAs were o...
Topics
- Base Sequence
- Endoribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA Precursors
- RNA Processing, Post-Transcriptional
- RNA, Bacterial
- RNA, Transfer
- Ribonuclease P
- Schizosaccharomyces
- Substrate Specificity
- Transcription, Genetic