Article
The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand.
The FEBS journal - 1 Nov 2006
Jones Grace, Jones Davy, Teal Peter, Sapa Agnes, Wozniak Mietek
Abstract excerpt
The in vivo ligand-binding function and ligand-binding activity of the Drosophila melanogaster retinoid-X receptor (RXR) ortholog, ultraspiracle, toward natural farnesoid products of the ring gland were assessed. Using an equilibrium fluorescence-binding assay, farnesoid products in the juvenile hormone (JH) biosynthesis pathway, and their epoxy derivatives, were measured for their affinity constant for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
