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Article

Ligand-binding properties of a juvenile hormone receptor, Methoprene-tolerant.

Proceedings of the National Academy of Sciences of the United States of America - 27 Dec 2011

Charles Jean-Philippe, Iwema Thomas, Epa V Chandana, Takaki Keiko, Rynes Jan, Jindra Marek

Abstract excerpt

Juvenile hormone (JH) is a sesquiterpenoid of vital importance for insect development, yet the molecular basis of JH signaling remains obscure, mainly because a bona fide JH receptor has not been identified. Mounting evidence points to the basic helix-loop-helix (bHLH)/Per-Arnt-Sim (PAS) domain protein Methoprene-tolerant (Met) as the best JH receptor candidate. However, details of how Met transduces the hormonal...

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Identifiers

PMID: 22167806
DOI: 10.1073/pnas.1116123109
PMCID: PMC3248530

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Ligand-binding properties of a juvenile hormone receptor, Methoprene-tolerant.PMID 22167806Read ↗

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Role of Methoprene-tolerant in the regulation of oogenesis in Dipetalogaster maximaSemantic proximity Read ↗

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