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Article

Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor.

Nature - 20 Sept 1990

Oro A E, McKeown M, Evans R M

Abstract excerpt

The vitamin A derivative, retinoic acid, can regulate morphogenesis and differentiation in vertebrates. Two different subfamilies of the steroid receptor superfamily of transcription factors, the retinoic acid receptors and the retinoid X receptor, mediate the effects of retinoic acid. As part of an analysis of the hormonal control of development, we have examined the Drosophila genome for retinoic acid receptor...

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PMID: 2169594
DOI: 10.1038/347298a0

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Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor.PMID 2169594Read ↗

The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis.Semantic proximity Read ↗

The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response.Semantic proximity Read ↗

Expression and function of the ultraspiracle (usp) gene during development of Drosophila melanogaster.Semantic proximity Read ↗

Analyzing the repressive function of ultraspiracle, the Drosophila RXR, in Drosophila eye development.Semantic proximity Read ↗

The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand.Semantic proximity Read ↗

Isoform-specific regulation of a steroid hormone nuclear receptor by an E3 ubiquitin ligase in Drosophila melanogaster.Semantic proximity Read ↗

Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle.Semantic proximity Read ↗

Tissue-autonomous EcR functions are required for concurrent organ morphogenesis in the Drosophila embryo.Semantic proximity Read ↗

SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.Semantic proximity Read ↗

A role for ultraspiracle, the Drosophila RXR, in morphogenetic furrow movement and photoreceptor cluster formation.Semantic proximity Read ↗

Sox14 is required for transcriptional and developmental responses to 20-hydroxyecdysone at the onset of drosophila metamorphosis.Semantic proximity Read ↗

Rapid divergence of the ecdysone receptor in Diptera and Lepidoptera suggests coevolution between ECR and USP-RXR.Semantic proximity Read ↗

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