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Article

Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor.

Nature - 20 Sept 1990

Oro A E, McKeown M, Evans R M

Abstract excerpt

The vitamin A derivative, retinoic acid, can regulate morphogenesis and differentiation in vertebrates. Two different subfamilies of the steroid receptor superfamily of transcription factors, the retinoic acid receptors and the retinoid X receptor, mediate the effects of retinoic acid. As part of an analysis of the hormonal control of development, we have examined the Drosophila genome for retinoic acid receptor...

Topics

Amino Acid Sequence
Animals
Base Sequence
Binding Sites
Carrier Proteins
DNA
Drosophila
Humans
Molecular Sequence Data
Mutation
Nucleic Acid Hybridization
Receptors, Retinoic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Restriction Mapping

Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 2169594
DOI: 10.1038/347298a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2169594-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor.PMID 2169594Read ↗

The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis.Semantic proximity Read ↗

The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response.Semantic proximity Read ↗

Expression and function of the ultraspiracle (usp) gene during development of Drosophila melanogaster.Semantic proximity Read ↗

Analyzing the repressive function of ultraspiracle, the Drosophila RXR, in Drosophila eye development.Semantic proximity Read ↗

The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand.Semantic proximity Read ↗

Isoform-specific regulation of a steroid hormone nuclear receptor by an E3 ubiquitin ligase in Drosophila melanogaster.Semantic proximity Read ↗

Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle.Semantic proximity Read ↗

Tissue-autonomous EcR functions are required for concurrent organ morphogenesis in the Drosophila embryo.Semantic proximity Read ↗

SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.Semantic proximity Read ↗

A role for ultraspiracle, the Drosophila RXR, in morphogenetic furrow movement and photoreceptor cluster formation.Semantic proximity Read ↗

Sox14 is required for transcriptional and developmental responses to 20-hydroxyecdysone at the onset of drosophila metamorphosis.Semantic proximity Read ↗

Rapid divergence of the ecdysone receptor in Diptera and Lepidoptera suggests coevolution between ECR and USP-RXR.Semantic proximity Read ↗

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