Article
A mutation in the receptor Methoprene-tolerant alters juvenile hormone response in insects and crustaceans.
Nature communications - 1 Jan 2013
Miyakawa Hitoshi, Toyota Kenji, Hirakawa Ikumi, Ogino Yukiko, Miyagawa Shinichi, Oda Shigeto, Tatarazako Norihisa, Miura Toru, Colbourne John K, Iguchi Taisen
Abstract excerpt
Juvenile hormone is an essential regulator of major developmental and life history events in arthropods. Most of the insects use juvenile hormone III as the innate juvenile hormone ligand. By contrast, crustaceans use methyl farnesoate. Despite this difference that is tied to their deep evolutionary divergence, the process of this ligand transition is unknown. Here we show that a single amino-acid substitution in...
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