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Article

Analyzing the repressive function of ultraspiracle, the Drosophila RXR, in Drosophila eye development.

Mechanisms of development - 1 Feb 2002

Ghbeish Nora, McKeown Michael

Abstract excerpt

Response to the insect hormone ecdysone is mediated by a nuclear receptor complex containing Ultraspiracle (USP) and the Ecdysone Receptor (EcR). Among other phenotypes, loss of functional USP in Drosophila eye development results in an accelerated morphogenetic furrow, although loss of ecdysone arrests the furrow. We have shown that USP both represses and activates a gene affecting furrow movement, the...

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PMID: 11804781
DOI: 10.1016/s0925-4773(01)00610-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Analyzing the repressive function of ultraspiracle, the Drosophila RXR, in Drosophila eye development.PMID 11804781Read ↗

The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response.Semantic proximity Read ↗

The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis.Semantic proximity Read ↗

Tissue-autonomous EcR functions are required for concurrent organ morphogenesis in the Drosophila embryo.Semantic proximity Read ↗

Expression and function of the ultraspiracle (usp) gene during development of Drosophila melanogaster.Semantic proximity Read ↗

Ecdysone pathway is required for furrow progression in the developing Drosophila eye.Semantic proximity Read ↗

Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor.Semantic proximity Read ↗

Cell-autonomous requirement of the USP/EcR-B ecdysone receptor for mushroom body neuronal remodeling in Drosophila.Semantic proximity Read ↗

SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.Semantic proximity Read ↗

Creation of EcR isoform-specific mutations in Drosophila melanogaster via local P element transposition, imprecise P element excision, and male recombination.Semantic proximity Read ↗

A role for ultraspiracle, the Drosophila RXR, in morphogenetic furrow movement and photoreceptor cluster formation.Semantic proximity Read ↗

Opportunistic binding of EcR to open chromatin drives tissue-specific developmental responsesSemantic proximity Read ↗

Downregulation of ultraspiracle gene expression delays pupal development in honeybees.Semantic proximity Read ↗

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