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Article

Functional plasminogen activator inhibitor-1 gene variants and breast cancer survival.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2006

Zhang Xianglan, Shu Xiao-Ou, Cai Qiuyin, Ruan ZhiXian, Gao Yu-Tang, Zheng Wei

Abstract excerpt

PURPOSE: Plasminogen activator inhibitor-1 (PAI-1) plays an important role in cancer invasion and metastasis. A common polymorphism (4G/5G) in the promoter region of the PAI-1 gene has been reported to influence transcription and plasma levels of PAI-1. We evaluated the association between PAI-1 4G/5G polymorphism and breast cancer survival in a population-based cohort of breast cancer patients. EXPERIMENTAL...

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Identifiers

PMID: 17062678
DOI: 10.1158/1078-0432.CCR-05-2851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional plasminogen activator inhibitor-1 gene variants and breast cancer survival.PMID 17062678Read ↗

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