Article
Haemolysis and perturbations in the systemic iron metabolism of suckling, copper-deficient mosaic mutant mice - an animal model of Menkes disease.
PloS one - 1 Jan 2014
Lenartowicz Małgorzata, Starzyński Rafał R, Krzeptowski Wojciech, Grzmil Paweł, Bednarz Aleksandra, Ogórek Mateusz, Pierzchała Olga, Staroń Robert, Gajowiak Anna, Lipiński Paweł
Abstract excerpt
The biological interaction between copper and iron is best exemplified by the decreased activity of multicopper ferroxidases under conditions of copper deficiency that limits the availability of iron for erythropoiesis. However, little is known about how copper deficiency affects iron homeostasis through alteration of the activity of other copper-containing proteins, not directly connected with iron metabolism,...
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