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Article

Tumor necrosis factor-alpha gene promoter polymorphism in patients with familial Mediterranean fever.

Clinical rheumatology - 1 Jun 2007

Celebi Kobak Arzu, Kobak Senol, Kabasakal Yasemin, Akarca Ulus Salih

Abstract excerpt

The proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) plays an important role on the course of disease in familial Mediterranean fever (FMF). TNF-alpha gene promoter polymorphism may be a marker of susceptibility and severity of FMF. The aim of this study is to evaluate both TNF-alpha/238 and TNF-alpha/308 genotypes and allelic distribution in patients with FMF. Forty-one FMF patients and 43...

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Source

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PMID: 17057944
DOI: 10.1007/s10067-006-0430-z

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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