Article
Importin-mediated nuclear translocation of galectin-3.
The Journal of biological chemistry - 22 Dec 2006
Nakahara Susumu, Hogan Victor, Inohara Hidenori, Raz Avraham
Abstract excerpt
Galectin-3 (Gal-3), a member of a beta-galactoside-binding protein family, is involved in RNA processing and cell cycle regulation through activation of transcription factors when translocated to the nucleus. We have previously shown that Gal-3 can import into the nucleus through at least two pathways; via passive diffusion and/or active transport (Nakahara, S., Oka, N., Wang, Y., Hogan, V., Inohara, H, and Raz,...
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