Article
Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s).
The Journal of biological chemistry - 14 Jan 2005
Kamada Shinji, Kikkawa Ushio, Tsujimoto Yoshihide, Hunter Tony
Abstract excerpt
Caspase-3 is thought to play an important role(s) in the nuclear morphological changes that occur in apoptotic cells and many nuclear substrates for caspase-3 have been identified despite the cytoplasmic localization of procaspase-3. Therefore, whether activated caspase-3 is localized in the nucl...
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