Article
HLA class II influences humoral autoimmunity in patients with type 2 autoimmune hepatitis.
Journal of hepatology - 1 Dec 2006
Djilali-Saiah Idriss, Fakhfakh Amin, Louafi Hamida, Caillat-Zucman Sophie, Debray Dominique, Alvarez Fernando
Abstract excerpt
BACKGROUND/AIMS: Type 2 autoimmune hepatitis (AIH) is characterized by the presence of anti-liver kidney microsome (anti-LKM-1) and/or anti-liver cytosol type 1 (anti-LC1) autoantibodies. However, the correlation between these autoantibodies and the genetic background has not been studied. METHODS: Frequencies of HLA class II alleles were compared between the 60 Caucasian children with type 2 AIH and 313 control...
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