Article
Measuring covariation in RNA alignments: physical realism improves information measures.
Bioinformatics (Oxford, England) - 15 Dec 2006
Lindgreen S, Gardner P P, Krogh A
Abstract excerpt
MOTIVATION: The importance of non-coding RNAs is becoming increasingly evident, and often the function of these molecules depends on the structure. It is common to use alignments of related RNA sequences to deduce the consensus secondary structure by detecting patterns of co-evolution. A central...
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