Article
Incorporating phylogenetic-based covarying mutations into RNAalifold for RNA consensus structure prediction.
BMC bioinformatics - 27 Apr 2013
Ge Ping, Zhang Shaojie
Abstract excerpt
BACKGROUND: RNAalifold, a popular computational method for RNA consensus structure prediction, incorporates covarying mutations into a thermodynamic model to fold the aligned RNA sequences. When quantifying covariance, it evaluates conserved signals of two aligned columns with base-pairing rules....
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