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Article

H2rs: deducing evolutionary and functionally important residue positions by means of an entropy and similarity based analysis of multiple sequence alignments.

BMC bioinformatics - 27 Apr 2014

Janda Jan-Oliver, Popal Ajmal, Bauer Jochen, Busch Markus, Klocke Michael, Spitzer Wolfgang, Keller Jörg, Merkl Rainer

Abstract excerpt

BACKGROUND: The identification of functionally important residue positions is an important task of computational biology. Methods of correlation analysis allow for the identification of pairs of residue positions, whose occupancy is mutually dependent due to constraints imposed by protein structu...

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Identifiers

PMID: 24766829
DOI: 10.1186/1471-2105-15-118
PMCID: PMC4021312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24766829-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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