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Article

Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).

Biological psychiatry - 1 Apr 2005

Raybould Rachel, Green Elaine K, MacGregor Stuart, Gordon-Smith Katherine, Heron Jess, Hyde Sally, Caesar Sian, Nikolov Ivan, Williams Nigel, Jones Lisa, O'Donovan Michael C, Owen Michael J, Jones Ian, Kirov George, Craddock Nick

Abstract excerpt

BACKGROUND: Several studies support the dysbindin (dystrobrevin binding protein 1) gene (DTNBP1) as a susceptibility gene for schizophrenia. We previously reported that variation at a specific 3-locus haplotype influences susceptibility to schizophrenia in a large United Kingdom (UK) Caucasian case-control sample. METHODS: Using similar methodology to our schizophrenia study, we have investigated this same...

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Source

Identifiers

PMID: 15820225
DOI: 10.1016/j.biopsych.2005.01.018

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).PMID 15820225Read ↗

Effect of 5-haplotype of dysbindin gene (DTNBP1) polymorphisms for the susceptibility to bipolar I disorder.Semantic proximity Read ↗

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No evidence for association of the dysbindin gene [DTNBP1] with schizophrenia in an Irish population-based study.Semantic proximity Read ↗

Dysbindin (DTNBP1)--a role in psychotic depression?Semantic proximity Read ↗

The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease.Semantic proximity Read ↗

DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene.Semantic proximity Read ↗

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.Semantic proximity Read ↗

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