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Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (DTNBP1) gene in the Irish study of high-density schizophrenia families.

Molecular psychiatry - 1 May 2003

van den Oord E J C G, Sullivan P F, Jiang Y, Walsh D, O'Neill F A, Kendler K S, Riley B P

Abstract excerpt

A recent report showed significant associations between several SNPs in a previously unknown EST cluster with schizophrenia. (1). The cluster was identified as the human dystrobrevin binding protein 1 gene (DTNBP1) by sequence database comparisons and homology with mouse DTNBP1. (2). However, the linkage disequilibrium (LD) among the SNPs in DTNBP1 as well as the pattern of significant SNP-schizophrenia...

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Source

Identifiers

PMID: 12808430
DOI: 10.1038/sj.mp.4001263

Genes

DTNBP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (DTNBP1) gene in the Irish study of high-density schizophrenia families.PMID 12808430Read ↗

Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).Semantic proximity Read ↗

The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample.Semantic proximity Read ↗

Association study of the dystrobrevin-binding gene with schizophrenia in Australian and Indian samples.Semantic proximity Read ↗

The dystrobrevin-binding protein 1 gene: features and networks.Semantic proximity Read ↗

Identifying potential risk haplotypes for schizophrenia at the DTNBP1 locus in Han Chinese and Scottish populations.Semantic proximity Read ↗

Association study between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia: a meta-analysis.Semantic proximity Read ↗

Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a bipolar case-control study (BACCS).Semantic proximity Read ↗

Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia.Semantic proximity Read ↗

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.Semantic proximity Read ↗

Analysis of HapMap tag-SNPs in dysbindin (DTNBP1) reveals evidence of consistent association with schizophrenia.Semantic proximity Read ↗

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.Semantic proximity Read ↗

Association of the DTNBP1 locus with schizophrenia in a U.S. population.Semantic proximity Read ↗

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