Article
Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort.
Diabetologia - 1 Jan 2007
van Vliet-Ostaptchouk J V, Shiri-Sverdlov R, Zhernakova A, Strengman E, van Haeften T W, Hofker M H, Wijmenga C
Abstract excerpt
AIM/HYPOTHESIS: A strong association between susceptibility to type 2 diabetes and common variants of transcription factor 7-like 2 (TCF7L2), encoding an enteroendocrine transcription factor involved in glucose homeostasis, has been reported in three different populations (Iceland, Denmark and USA) by Grant et al. We aimed to replicate these findings in a Dutch cohort. METHODS: We analysed the genotypes of two...
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