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Article

The fundamental building blocks of cortical development are established in human exencephaly.

Pediatric research - 1 Apr 2020

Falcone Carmen, Vakilzadeh Gelareh, Noctor Stephen C, Martínez-Cerdeño Verónica

Abstract excerpt

BACKGROUND: The presence and status of progenitor/stem cells in excencephalic brain have not been previously examined. METHODS: Brain sections of excencephalic 17-week fetus were stained for specific stem and mature cell markers. RESULTS: The ventricles were open, the developing cerebral cortex was thin in the radial dimension, and the ventricular surface was undulated. There was a decreased ratio of...

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PMID: 31783397
DOI: 10.1038/s41390-019-0687-y

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