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Article

Histone modifications in Duchenne muscular dystrophy: pathogenesis insights and therapeutic implications.

Journal of medical genetics - 23 Oct 2024

Wei Yanning, Jiang Yuanyuan, Lu Yufei, Hu Qiping

Abstract excerpt

Duchenne muscular dystrophy (DMD) is a commonly encountered genetic ailment marked by loss-of-function mutations in the Dystrophin gene, ultimately resulting in progressive debilitation of skeletal muscle. The investigation into the pathogenesis of DMD has increasingly converged on the role of histone modifications within the broader context of epigenetic regulation. These modifications, including histone...

Read the complete abstract on PubMed

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Share to Acetylation
Share to Dystrophin
Share to Histone Code

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histones

Share to Methylation

Share to Muscle, Skeletal

Share to Muscular Dystrophy, Duchenne

Share to Protein Processing, Post-Translational

Source

Identifiers

PMID: 39327039
DOI: 10.1136/jmg-2024-110045

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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