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Article

Role of pairwise interactions between M1 and M2 domains of the nicotinic receptor in channel gating.

Biophysical journal - 1 Jan 2007

Corradi Jeremías, Spitzmaul Guillermo, De Rosa María José, Costabel Marcelo, Bouzat Cecilia

Abstract excerpt

The adult form of the nicotinic acetylcholine receptor (AChR) consists of five subunits (alpha(2)betaepsilondelta), each having four transmembrane domains (M1-M4). The atomic model of the nicotinic acetylcholine receptor shows that the pore-lining M2 domains make no extensive contacts with the re...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17028140
DOI: 10.1529/biophysj.106.088757
PMCID: PMC1697868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17028140-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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