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Article

Expression of C-terminal deleted p53 isoforms in neuroblastoma

5 Oct 2006

Abstract excerpt

The tumor suppressor gene, p53, is rarely mutated in neuroblastomas (NB) at the time of diagnosis, but its dysfunction could result from a nonfunctional conformation or cytoplasmic sequestration of the wild-type p53 protein. However, p53 mutation, when it occurs, is found in NB tumors with drug resistance acquired over the course of chemotherapy. As yet, no study has been devoted to the function of the specific...

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Identifiers

PMID: 17028100
DOI: 10.1093/nar/gkl619

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of C-terminal deleted p53 isoforms in neuroblastomaPMID 17028100Read ↗

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