Article
Xenopus fibrillin regulates directed convergence and extension.
Developmental biology - 15 Jan 2007
Skoglund Paul, Keller Ray
Abstract excerpt
Fibrillin-based human diseases such as Marfan syndrome and congenital contractural arachnodactyly implicate fibrillins in the function and homeostasis of multiple adult tissues. Fibrillins are also expressed in embryos, but no early developmental role has been described for these proteins. We use three independent methods to reveal a role for Xenopus fibrillin (XF) at gastrulation. First, expressing truncated...
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