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Article

Identification and characterization of "pathoadaptive mutations" of the cadBA operon in several intestinal Escherichia coli.

International journal of medical microbiology : IJMM - 1 Dec 2006

Jores Joerg, Torres Alfredo G, Wagner Sylke, Tutt Christopher B, Kaper James B, Wieler Lothar H

Abstract excerpt

The dysenteric Shigella spp. and enteroinvasive Escherichia coli (EIEC) have evolved from commensal E. coli by the acquisition of a virulence plasmid and inactivation of genes of the cad locus encoding lysine decarboxylase (LDC) by so-called pathoadaptive mutation. As horizontal gene transfer and recombination occurs frequently in E. coli we were interested to see if similar pathoadaptive mutations are commonly...

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Identifiers

PMID: 17027337
DOI: 10.1016/j.ijmm.2006.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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