Article
Identification and characterization of "pathoadaptive mutations" of the cadBA operon in several intestinal Escherichia coli.
International journal of medical microbiology : IJMM - 1 Dec 2006
Jores Joerg, Torres Alfredo G, Wagner Sylke, Tutt Christopher B, Kaper James B, Wieler Lothar H
Abstract excerpt
The dysenteric Shigella spp. and enteroinvasive Escherichia coli (EIEC) have evolved from commensal E. coli by the acquisition of a virulence plasmid and inactivation of genes of the cad locus encoding lysine decarboxylase (LDC) by so-called pathoadaptive mutation. As horizontal gene transfer and...
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