Article
CadC has a global translational effect during acid adaptation in Salmonella enterica serovar Typhimurium.
Journal of bacteriology - 1 Mar 2007
Lee Yong Heon, Kim Bae Hoon, Kim Ji Hye, Yoon Won Suck, Bang Seong Ho, Park Yong Keun
Abstract excerpt
In Salmonella enterica serovar Typhimurium, the membrane-localized CadC is a transcriptional activator of the cadBA operon, which contributes to the acid tolerance response. Unlike in Escherichia coli, in which transcription of cadC is constitutive, in S. enterica serovar Typhimurium cadC expression is induced by low pH and lysine. Inactivation of cadC suppresses the acid-sensitive phenotype of a cadA mutation,...
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