Association analysis of NAD(P)H:quinone oxidoreductase gene 609 C/T polymorphism with Alzheimer's disease.

doi:10.1016/j.neulet.2006.09.042

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Association analysis of NAD(P)H:quinone oxidoreductase gene 609 C/T polymorphism with Alzheimer's disease.

Neuroscience letters - 6 Dec 2006

Wang Binbin, Jin Feng, Xie Yanchen, Tang Ying, Kan Rui, Zheng Chenguang, Yang Ze, Wang Li

Abstract excerpt

Alterations of the NAD(P)H:quinone oxidoreductase (NQO1) activity are associated with Alzheimer's disease (AD). A polymorphism consisting of a single nucleotide (C-->T) change at position 609 of NQO1 influences the NQO1 activity. Therefore the NQO1 C609T polymorphism may confer susceptibility for AD developing. To test the hypothesis, we have performed an association study between the NQO1 gene polymorphism C609T...

Topics

Aged
Aged, 80 and over
Alzheimer Disease
China
DNA Mutational Analysis
Female
Genetic Predisposition to Disease
Genetic Testing
Heterozygote
Humans
Incidence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

NAD(P)H Dehydrogenase (Quinone)

Polymorphism, Single Nucleotide

Risk Assessment

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 17027152
DOI: 10.1016/j.neulet.2006.09.042

Genes

NQO1
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17027152-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association analysis of NAD(P)H:quinone oxidoreductase gene 609 C/T polymorphism with Alzheimer's disease.PMID 17027152Read ↗

Association of NAD(P)H:quinone oxidoreductase 1 polymorphism and Alzheimer's disease in Chinese.Semantic proximity Read ↗

Association of the NQO1 C609T polymorphism with Alzheimer's disease in Chinese populations: a meta-analysis.Semantic proximity Read ↗

[NQ01 gene polymorphism C609T associated with an increased risk for cognitive dysfunction and sporadic Alzheimer's disease in Chinese].Semantic proximity Read ↗

[Association between NAD(P)H: quinone oxidoreductase and apolipoprotein E gene polymorphisms in Alzheimer's disease].Semantic proximity Read ↗

The NAD(P)H: quinine oxidoreductase 1 (NQO1) gene 609 C>T polymorphism is associated with gastric cancer risk: evidence from a case-control study and a meta-analysis.Semantic proximity Read ↗

Association of the NAD(P)H:quinone oxidoreductase (NQO1) 609C->T polymorphism with lung cancer risk among male smokers.Semantic proximity Read ↗

A functional NQO1 609C>T polymorphism and risk of hepatocellular carcinoma in a Chinese population.Semantic proximity Read ↗

The C609T inborn polymorphism in NAD(P)H:quinone oxidoreductase 1 is associated with susceptibility to multiple sclerosis and affects the risk of development of the primary progressive form of the disease.Semantic proximity Read ↗

Association of the NAD(P)H:quinone oxidoreductase 609C-->T polymorphism with a decreased lung cancer risk.Semantic proximity Read ↗

NQO1 C609T Polymorphism is Associated with Coronary Artery Disease in a Gender-Dependent Manner.Semantic proximity Read ↗

Meta-analysis demonstrates that the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene 609 C>T polymorphism is associated with increased gastric cancer risk in Asians.Semantic proximity Read ↗

Association between NOS3 gene G894T polymorphism and late-onset Alzheimer disease in a sample from Iran.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.