Article
Meta-analysis demonstrates that the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene 609 C>T polymorphism is associated with increased gastric cancer risk in Asians.
Genetics and molecular research : GMR - 13 Aug 2012
Zhang Y, Wang Z T, Zhong J
Abstract excerpt
The association between the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene C609T polymorphism and gastric cancer has been widely evaluated, yet with conflicting results. Data were available from seven study populations involving 2600 subjects. Overall, comparison of alleles 609T and 609C indicated a significantly increased risk (46%) for gastric cancer (95% confidence interval (95%CI) for odds ratio (OR) =...
Topics
- Asian People
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- NAD(P)H Dehydrogenase (Quinone)
- Polymorphism, Single Nucleotide
- Risk Factors
- Stomach Neoplasms