Article
[Association between NAD(P)H: quinone oxidoreductase and apolipoprotein E gene polymorphisms in Alzheimer's disease].
Zhonghua yi xue za zhi - 25 Dec 2003
Ma Qiu-lan, Yang Jing-fang, Shao Ming, Dong Xiu-min, Chen Biao
Abstract excerpt
OBJECTIVE: To assess the association between NAD(P)H: quinone oxidoreductase 1 (NQO1) C609 T allele and apolipoprotein E (ApoE) polymorphism and sporadic Alzheimer disease (SAD). METHODS: The polymorphisms of NQO1 and ApoE gene were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 92 SAD patients and 108 normal controls, all of Han nationality. RESULTS: The...
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Apolipoproteins E
- Female
- Genotype
- Humans
- Male
- Middle Aged
- NAD(P)H Dehydrogenase (Quinone)
- Polymorphism, Genetic
