Article
IFN gamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis.
Tissue antigens - 1 Oct 2006
Boyton R J, Reynolds C, Wahid F N, Jones M G, Ozerovitch L, Ahmad T, Chaudhry A, Jewell D P, Kon O M, Smith J, Rose M, Newman-Taylor A J, Cole P, Wilson R, Altmann D M
Abstract excerpt
Idiopathic bronchiectasis is a disease of chronic, bacterial lung infection, unresolving inflammation and progressive lung damage. Bronchiectasis can be associated with autoimmune diseases including ulcerative colitis. Defects of both innate and adaptive immunity have been proposed. The airway inflammation is characterized by interleukin-8 (IL-8) expression and infiltration by neutrophils and T cells. Here we...
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