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Article

Effect of +36T>C in intron 1 on the glutamine: fructose-6-phosphate amidotransferase 1 gene and its contribution to type 2 diabetes in different populations.

Journal of human genetics - 1 Jan 2006

Kunika Kiyoshi, Tanahashi Toshihito, Kudo Eiji, Mizusawa Noriko, Ichiishi Eiichiro, Nakamura Naoto, Yoshikawa Toshikazu, Yamaoka Takashi, Yasumo Hiroaki, Tsugawa Kazue, Moritani Maki, Inoue Hiroshi, Itakura Mitsuo

Abstract excerpt

Glutamine: fructose-6-phosphate amidotransferase 1 (GFPT1) acts as a rate-limiting enzyme in the hexosamine biosynthetic pathway, which is an alternative branch of glucose metabolism. To evaluate GFPT1 as a susceptibility gene to type 2 diabetes, we surveyed the polymorphisms related with the gen...

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Identifiers

PMID: 17024311
DOI: 10.1007/s10038-006-0072-7

Genes

GFPT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17024311-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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