Distinct glycoprotein inhibitors of influenza A virus in different animal sera.

doi:10.1128/JVI.65.1.389-395.1991

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Article

Distinct glycoprotein inhibitors of influenza A virus in different animal sera.

Journal of virology - 1 Jan 1991

Ryan-Poirier K A, Kawaoka Y

Abstract excerpt

Normal horse and guinea pig sera contain the glycoprotein inhibitor alpha 2-macroglobulin, which inhibits the infectivity and hemagglutinating activity of influenza A viruses of the H2 and H3 subtypes. In the current study, the presence of inhibitors of influenza A virus in pig and rabbit sera was investigated. Variants of influenza virus type A/Los Angeles/2/87(H3N2) that were resistant to horse, pig, or rabbit...

Topics

Amino Acid Sequence
Animals
Chick Embryo
Genes, Viral
Genetic Variation
Glycosylation
Hemagglutination, Viral
Hemagglutinin Glycoproteins, Influenza Virus
Hemagglutinins, Viral
Horses
Influenza A virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Molecular

Neutralization Tests

Protein Conformation

Rabbits

Species Specificity

Swine

alpha-Macroglobulins

Source

Open in PubMed Open full text

Identifiers

PMID: 1702161
DOI: 10.1128/JVI.65.1.389-395.1991
PMCID: PMC240529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1702161-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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