Article
Identification of amino acids in H9N2 influenza virus neuraminidase that are critical for the binding of two mouse monoclonal antibodies.
Veterinary microbiology - 1 May 2016
Wan Zhimin, Ye Jianqiang, Sang Jianjun, Shao Hongxia, Qian Kun, Jin Wenjie, Qin Aijian, Wan Hongquan
Abstract excerpt
Neuraminidase (NA) is one of the major glycoproteins on the surface of influenza virus. It cleaves the linkage between haemagglutinin and cell surface receptors, and thus helps the release and spread of influenza virus. Despite the importance of H9N2 virus in influenza pandemic preparedness, the antigenic characteristics of its surface glycoproteins, especially NA, remains to be investigated. In the present...
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