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Article

Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia.

Journal of the National Cancer Institute - 4 Oct 2006

Verrills Nicole M, Po'uha Sela T, Liu Marjorie L M, Liaw Tracy Y E, Larsen Martin R, Ivery Michael T, Marshall Glenn M, Gunning Peter W, Kavallaris Maria

Abstract excerpt

BACKGROUND: Proteomic investigations have revealed alterations in cytoskeletal proteins expressed in human acute lymphoblastic leukemia cells that are resistant to microtubule-disrupting agents. We characterized gamma-actin expression in antimicrotubule drug-resistant leukemia and examined the effect of altered gamma-actin in resistance of acute lymphoblastic leukemia to antimicrotubule agents. METHODS:...

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Identifiers

PMID: 17018783
DOI: 10.1093/jnci/djj372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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