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Article

Evaluating candidate agents of selective pressure for cystic fibrosis.

Journal of the Royal Society, Interface - 22 Feb 2007

Poolman Eric M, Galvani Alison P

Abstract excerpt

Cystic fibrosis is the most common lethal single-gene mutation in people of European descent, with a carrier frequency upwards of 2%. Based upon molecular research, resistances in the heterozygote to cholera and typhoid fever have been proposed to explain the persistence of the mutation. Using a...

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Identifiers

PMID: 17015291
DOI: 10.1098/rsif.2006.0154
PMCID: PMC2358959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17015291-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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