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Article

An evolutionary approach to the high frequency of the Delta F508 CFTR mutation in European populations.

Medical hypotheses - 1 Jun 2010

Alfonso-Sánchez Miguel A, Pérez-Miranda Ana M, García-Obregón Susana, Peña José A

Abstract excerpt

The diffusion of the cattle pastoralism across Europe during the Neolithic period was probably accompanied by the emergence and spread of diverse contagious diseases that were unknown in the Paleolithic and that would have affected the frequency of genes directly or indirectly associated with differential susceptibility and/or resistance to infectious pathogens. We therefore propose that the high frequency of the...

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Source

Identifiers

PMID: 20110149
DOI: 10.1016/j.mehy.2009.12.018

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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