Article
Growth control in the proliferative region of the Drosophila eye-head primordium: the elbow-noc gene complex.
Developmental biology - 15 Jan 2007
Luque Carlos M, Milán Marco
Abstract excerpt
Notch signaling is involved in cell differentiation and patterning, as well as in the regulation of growth and cell survival. Notch activation at the dorsal-ventral boundary of the Drosophila eye-head primordium leads to the expression of the secreted protein Unpaired, a ligand of the JAK-STAT pathway that induces cell proliferation in the undifferentiated tissue. The zinc finger proteins encoded by elbow and no...
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