EYA4, a novel vertebrate gene related to Drosophila eyes absent.

doi:10.1093/hmg/8.1.11

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Article

EYA4, a novel vertebrate gene related to Drosophila eyes absent.

Human molecular genetics - 1 Jan 1999

Borsani G, DeGrandi A, Ballabio A, Bulfone A, Bernard L, Banfi S, Gattuso C, Mariani M, Dixon M, Donnai D, Metcalfe K, Winter R, Robertson M, Axton R, Brown A, van Heyningen V, Hanson I

Abstract excerpt

We have isolated a family of four vertebrate genes homologous to eyes absent (eya), a key regulator of ocular development in Drosophila. Here we present the detailed characterization of the EYA4 gene in human and mouse. EYA4 encodes a 640 amino acid protein containing a highly conserved C-termina...

Topics

Alternative Splicing
Amino Acid Sequence
Animals
Base Sequence
Chromosome Mapping
DNA, Complementary
Drosophila
Drosophila Proteins
Eye
Eye Abnormalities
Eye Proteins
Genes, Insect
Humans
In Situ Hybridization

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Molecular Sequence Data

Mutation

Sequence Homology, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 9887327
DOI: 10.1093/hmg/8.1.11

Genes

EYA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9887327-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.