Article
Passive stiffness in Drosophila indirect flight muscle reduced by disrupting paramyosin phosphorylation, but not by embryonic myosin S2 hinge substitution.
Biophysical journal - 15 Dec 2006
Hao Yudong, Miller Mark S, Swank Douglas M, Liu Hongjun, Bernstein Sanford I, Maughan David W, Pollack Gerald H
Abstract excerpt
High passive stiffness is one of the characteristic properties of the asynchronous indirect flight muscle (IFM) found in many insects like Drosophila. To evaluate the effects of two thick filament protein domains on passive sarcomeric stiffness, and to investigate their correlation with IFM function, we used microfabricated cantilevers and a high resolution imaging system to study the passive IFM myofibril...
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