Article
A non-flight muscle isoform of Drosophila tropomyosin rescues an indirect flight muscle tropomyosin mutant.
Journal of muscle research and cell motility - 1 Feb 1993
Miller R C, Schaaf R, Maughan D W, Tansey T R
Abstract excerpt
The tropomyosin I(TmI) gene of Drosophila melanogaster encodes two isoforms of tropomyosin. The Ifm-TmI isoform is expressed only in indirect flight and jump muscles; the Scm-TmI isoform is found in other muscles of the larva and adult. The level of Ifm-TmI is severely reduced in the flightless mutant Ifm(3)3, which also is unable to jump. To explore the functional significance of tropomyosin isoform diversity in...
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