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Article

Mutations of TGFbeta signaling molecules in human disease.

Annals of medicine - 1 Jan 2006

Harradine Kelly A, Akhurst Rosemary J

Abstract excerpt

The transforming growth factor beta (TGFbeta) signaling pathway regulates several biological processes including cellular proliferation, differentiation, apoptosis, migration, and extracellular matrix deposition. Ligand and receptor family members signal through two main Smad signaling branches, TGFbeta/activin to Smad2/3 (Sma and MAD-related proteins) and bone morphogenetic protein (BMP) to Smad1/5. At the...

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Source

Identifiers

PMID: 17008304
DOI: 10.1080/07853890600919911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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