Article
Chromosome segregation in fission yeast with mutations in the tubulin folding cofactor D.
Current genetics - 1 Nov 2006
Fedyanina Olga S, Mardanov Pavel V, Tokareva Ekaterina M, McIntosh J Richard, Grishchuk Ekaterina L
Abstract excerpt
Faithful chromosome segregation requires the combined activities of the microtubule-based mitotic spindle and the multiple proteins that form mitotic kinetochores. Here, we show that the fission yeast mitotic mutant, tsm1-512, is an allele of the tubulin folding chaperone, cofactor D. Chromosome segregation in this and in an additional cofactor D mutant depends on growth conditions that are monitored specifically...
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